This paper presents a quantitative assessment framework of the Water, Energy and Food (W-E-F) nexus. The proposed approach allows integrated quantitative assessments by considering all the W-E-F intersectoral linkages and the competing demand for W-E-F resources to evaluate future development scenarios. Firstly, the conceptual model adopted for the proposed framework is presented. Secondly, a detailed methodological framework is introduced to serve as W-E-F nexus evaluation and planning platform. At the practical level, the model is applied to evaluate the W-E-F nexus in Lebanon. Finally, the conclusions and further developments are presented.